EPS15 Antikörper (C-Term)

Produktnummer ABIN2785791

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch EPS15 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für EPS15 Antikörper (C-Term) (ABIN2785791)

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPS15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EPS15 Antikörper

Bindungsspezifität: C-Term

Sequenz: LDSPDPFKLN DPFQPFPGND SPKEKDPEIF CDPFTSATTT TNKEADPSNF

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EPS15. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EPS15

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 896 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EPS15

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Andere Bezeichnung: EPS15

Hintergrund: EPS15 is a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias.This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AF-1P, AF1P, MLLT5
Protein Interaction Partner: TRIM63, UBC, GJA1, EPHA2, CORO7, RNF11, RABL6, OPTN, LAPTM5, VCAM1, ITGA4, FN1, Fcho2, Dab2, STON2, EPN1, AGFG1, EPS15, CRKL, CRK, AP2S1, AP2M1, AP2B1, AP1B1, AP2A2, AP2A1, ACTB, ABL1, NECAP1, SPG20, VPRBP, KRT75, IQGAP1, KRT36, KRT37, KRT38, CCT3, TRAF2,
Protein Size: 896

Molekulargewicht: 99 kDa

Gen-ID: 2060

NCBI Accession: NM_001981, NP_001972

UniProt: P42566

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation