SH3KBP1 Antikörper (N-Term)

Produktnummer ABIN2785720

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SH3KBP1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für SH3KBP1 Antikörper (N-Term) (ABIN2785720)

Target: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3KBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SH3KBP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: TGMFPSNFIK ELSGESDELG ISQDEQLSKS SLRETTGSES DGGDSSSTKS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SH3KBP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SH3KBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 628 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SH3KBP1

Target: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Andere Bezeichnung: SH3KBP1

Hintergrund: This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
Alias Symbols: CIN85, GIG10, MIG18, HSB1, HSB-1, CD2BP3
Protein Interaction Partner: PNMA5, ZBTB7B, SH3KBP1, STAP1, FRS3, SPRY2, ASAP2, PSMA3, CBL, UBC, RAF1, LOX, INPP5D, Dlg4, FAP, ARHGAP17, Ap2a1, Irf2bp1, Gcdh, Sept7, Wipf1, Chtf8, Cblb, Shkbp1, Rtkn2, Idh3b, Pik3ap1, Slc25a12, Wasl, Ap2b1, Arap1, Far1, Cltc, Timm50, Actn4, Sept6, Net
Protein Size: 628

Molekulargewicht: 68 kDa

Gen-ID: 30011

NCBI Accession: NM_001024666, NP_001019837

UniProt: Q5JPT5

Pathways: EGFR Signaling Pathway, EGFR Downregulation