ATG16L1 Antikörper (Middle Region)

Produktnummer ABIN2785624

Der Kaninchen Polyklonal anti-ATG16L1 Antikörper (ABIN2785624) detektiert spezifisch ATG16L1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen und Schwein.

Kurzübersicht für ATG16L1 Antikörper (Middle Region) (ABIN2785624)

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG16L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATG16L1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: ATG16L1 Antibody - middle region

Sequenz: TSPVRAISRA ATKRLSQPAG GLLDSITNIF GRRSVSSFPV PQDNVDTHPG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG16L1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG16L1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095131

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG16L1

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Andere Bezeichnung: ATG16L1

Hintergrund:

Background Information: Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).[supplied by OMIM].

Gene Name: ATG16 autophagy related 16-like 1 (S. cerevisiae)

Alternative Symbols: IBD10, WDR30, APG16L, ATG16A, ATG16L

Protein Name: Autophagy-related protein 16-1

Molekulargewicht: 68kDa

Gen-ID: 55054

NCBI Accession: NP_110430

UniProt: Q676U5

Pathways: Autophagie