ATG16L1 Antikörper (N-Term)

Produktnummer ABIN2785621

Der Kaninchen Polyklonal Anti-ATG16L1 Antikörper wurde für WB und IHC validiert. Er ist geeignet, ATG16L1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen und Meerschweinchen zu detektieren.

Kurzübersicht für ATG16L1 Antikörper (N-Term) (ABIN2785621)

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG16L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ATG16L1 Antikörper

Bindungsspezifität: N-Term

Sequenz: QYNKLLEKSD LHSVLAQKLQ AEKHDVPNRH EISPGHDGTW NDNQLQEMAQ

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 91%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG16L1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATG16L1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 588 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG16L1

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Andere Bezeichnung: ATG16L1

Hintergrund: Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).[supplied by OMIM].
Alias Symbols: APG16L, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30, ATG16A
Protein Interaction Partner: WIPI2, RB1CC1, DEDD2, TRAF3IP3, NOD2, TMEM59, TLR2, SUMO2, ATG13, ATG5, ULK1, UBC, TNK2, SYNPO2, ATG12, NOD1, WDFY3, APP, RAB33B, RAB35, RAB3D, RAB33A, HSPA4, FCGRT, CLTC, AP2M1, ELAVL1, MAP1LC3C, MAP1LC3B, ATG3, CCT2, CCT7, AGPS, GAN, CCT3, SNAPC4, ATG16
Protein Size: 588

Molekulargewicht: 66 kDa

Gen-ID: 55054

NCBI Accession: NM_017974, NP_060444

UniProt: Q676U5

Pathways: Autophagie