ATG16L1 Antikörper (N-Term)

Produktnummer ABIN2785621

Der Kaninchen Polyklonal Anti-ATG16L1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ATG16L1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen und Meerschweinchen zu detektieren.

Kurzübersicht für ATG16L1 Antikörper (N-Term) (ABIN2785621)

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG16L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ATG16L1 Antikörper

Bindungsspezifität: N-Term

Sequenz: QYNKLLEKSD LHSVLAQKLQ AEKHDVPNRH EISPGHDGTW NDNQLQEMAQ

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 91%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG16L1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATG16L1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 588 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG16L1

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Andere Bezeichnung: ATG16L1

Hintergrund: Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).[supplied by OMIM].
Alias Symbols: APG16L, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30, ATG16A
Protein Interaction Partner: WIPI2, RB1CC1, DEDD2, TRAF3IP3, NOD2, TMEM59, TLR2, SUMO2, ATG13, ATG5, ULK1, UBC, TNK2, SYNPO2, ATG12, NOD1, WDFY3, APP, RAB33B, RAB35, RAB3D, RAB33A, HSPA4, FCGRT, CLTC, AP2M1, ELAVL1, MAP1LC3C, MAP1LC3B, ATG3, CCT2, CCT7, AGPS, GAN, CCT3, SNAPC4, ATG16
Protein Size: 588

Molekulargewicht: 66 kDa

Gen-ID: 55054

NCBI Accession: NM_017974, NP_060444

UniProt: Q676U5

Pathways: Autophagie