Aurora A Antikörper (Middle Region)

Produktnummer ABIN2785452

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Aurora A in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Schaf, Kaninchen, Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für Aurora A Antikörper (Middle Region) (ABIN2785452)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Aurora A Antikörper

Bindungsspezifität: Middle Region

Sequenz: REKQSKFILA LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against AURKA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human AURKA

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Andere Bezeichnung: AURKA

Hintergrund: AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Alias Symbols: AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7
Protein Interaction Partner: CHFR, GADD45A, RPLP2, RPLP0, RPL38, RPL30, RPL27, RPL22, RPL12, RPL11, PSMB7, PSMB5, PSMA6, PSMA5, PSMA1, MAPK6, PPP6C, PCMT1, YBX1, NPM1, NCL, MFAP4, LYZ, ILF3, ILF2, IARS, HSPD1, HSP90AB1, HSP90AA1, HSPA9, HSPA8, HSPA5, HSPA2, HSPA1A, HNRNPU, HNRNPA2B1,
Protein Size: 403

Molekulargewicht: 44 kDa

Gen-ID: 6790

NCBI Accession: NM_198437, NP_940839

UniProt: O14965

Pathways: Zellzyklus, Asymmetric Protein Localization