GRPEL2 Antikörper (Middle Region)
Kurzübersicht für GRPEL2 Antikörper (Middle Region) (ABIN2785166)
Target
Alle GRPEL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Middle Region
-
Verwendungszweck
- GRPEL2 Antibody - middle region
-
Sequenz
- HEHELICHVP AGVGVQPGTV ALVRQDGYKL HGRTIRLARV EVAVESQRRL
-
Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against GRPEL2. It was validated on Western Blot using a cell lysate as a positive control.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GRPEL2
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52949-100UG
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- prevent freeze-thaw cycles
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))
-
Andere Bezeichnung
- GRPEL2
-
Hintergrund
-
Background Information: GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Gene Name: GrpE-like 2, mitochondrial (E. coli)
Alternative Symbols: Mt-GrpE#2
Protein Name: GrpE protein homolog 2, mitochondrial
-
Molekulargewicht
- 25kDa
-
Gen-ID
- 134266
-
NCBI Accession
- NP_689620
-
UniProt
- Q8TAA5
Target
-