DYNC1I2 Antikörper (N-Term)

Produktnummer ABIN2784706

Produktdetails anti-DYNC1I2 Antikörper

Target: DYNC1I2 (Dynein, Cytoplasmic 1, Intermediate Chain 2 (DYNC1I2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYNC1I2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VAPKPPIEPE EEKTLKKDEE NDSKAPPHEL TEEEKQQILH SEEFLSFFDH

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DYNC1I2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DYNC1I2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 638 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DYNC1I2

Target: DYNC1I2 (Dynein, Cytoplasmic 1, Intermediate Chain 2 (DYNC1I2))

Andere Bezeichnung: DYNC1I2 (DYNC1I2 Produkte)

Synonyme: dnci2 antikoerper, dncic1 antikoerper, ic2 antikoerper, dync1i2 antikoerper, im:7147021 antikoerper, zgc:153318 antikoerper, 3110079H08Rik antikoerper, AW554389 antikoerper, Dncic2 antikoerper, Dnci2 antikoerper, DNCI2 antikoerper, IC2 antikoerper, dynein, cytoplasmic 1, intermediate chain 2 antikoerper, dynein, cytoplasmic 1, intermediate chain 2 S homeolog antikoerper, dynein cytoplasmic 1 intermediate chain 2 antikoerper, dynein, cytoplasmic 1, intermediate chain 2a antikoerper, dync1i2 antikoerper, dync1i2.S antikoerper, DYNC1I2 antikoerper, dync1i2a antikoerper, Dync1i2 antikoerper

Hintergrund: DYNC1I2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.
Alias Symbols: DNCI2, FLJ21089, FLJ90842, IC2, MGC104199, MGC111094, MGC9324
Protein Interaction Partner: DYNLRB1, TUBGCP3, SUMO2, UBC, RNF2, EIF3CL, PRUNE2, DYNC1LI1, EIF3K, SERBP1, HNRNPA0, AKAP12, EIF3G, EIF3B, EIF3A, RPS26, RPS13, RPS5, PSMD8, PSMC5, YBX1, MAP2, DYNC1LI2, DYNC1H1, DDX1, ABCF1, vpr, PEX14, VCP, ECT2, CUL3, Dynll1, Dync1i2, SRRM2, DCTN1, PN
Protein Size: 638

Molekulargewicht: 71 kDa

Gen-ID: 1781

NCBI Accession: NM_001378, NP_001369

UniProt: Q13409

Pathways: M Phase