ALKBH2 Antikörper (Middle Region)
Kurzübersicht für ALKBH2 Antikörper (Middle Region) (ABIN2784623)
Target
Alle ALKBH2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- VPRKQATYGD AGLTYTFSGL TLSPKPWIPV LERIRDHVSG VTGQTFNFVL
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ALKBH2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ALKBH2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 261 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))
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Andere Bezeichnung
- ALKBH2
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Hintergrund
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The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM].
Alias Symbols: ABH2, MGC90512, hABH2
Protein Interaction Partner: UBC,
Protein Size: 261 -
Molekulargewicht
- 29 kDa
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Gen-ID
- 121642
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NCBI Accession
- NM_001001655, NP_001001655
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UniProt
- Q6NS38
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Pathways
- DNA Reparatur
Target
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