MDFIC Antikörper (Middle Region)

Produktnummer ABIN2784370

Dieses Anti-MDFIC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MDFIC in WB. Geeignet für Human, Kaninchen, Rind (Kuh), Schwein, Hund, Pferd und Ratte.

Kurzübersicht für MDFIC Antikörper (Middle Region) (ABIN2784370)

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Reaktivität: Human, Kaninchen, Rind (Kuh), Schwein, Hund, Pferd, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFIC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MDFIC Antikörper

Bindungsspezifität: Middle Region

Sequenz: PQLQTSAQVP SGEEIGKIKN GHTGLSNGNG IHHGAKHGSA DNRKLSAPVS

Homologie: Cow: 79%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 86%, Rabbit: 93%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MDFIC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MDFIC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 355 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MDFIC

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Andere Bezeichnung: MDFIC

Hintergrund: MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.
Alias Symbols: HIC
Protein Interaction Partner: SOCS4, tat, RPS6KA5, CSNK2A1, MDFIC, CDK9, CCNT1,
Protein Size: 355

Molekulargewicht: 37 kDa

Gen-ID: 29969

NCBI Accession: NM_199072, NP_951038

UniProt: Q9P1T7