MDFIC Antikörper (AA 35-53)

Produktnummer ABIN7139928

Produktdetails anti-MDFIC Antikörper

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Bindungsspezifität: AA 35-53

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFIC Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Peptide sequence from Human MyoD family inhibitor domain-containing protein (35-53AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MDFIC

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Andere Bezeichnung: MDFIC (MDFIC Produkte)

Synonyme: HIC antikoerper, Kdt1 antikoerper, Mdfid antikoerper, MyoD family inhibitor domain containing antikoerper, MyoD family inhibitor domain containing S homeolog antikoerper, MDFIC antikoerper, Mdfic antikoerper, mdfic.S antikoerper

Hintergrund:

Background: Acts as a transcriptional activator or repressor. Inhibits the transcriptional activation of Zic family proteins ZIC1, ZIC2 and ZIC3. Retains nuclear Zic proteins ZIC1, ZIC2 and ZIC3 in the cytoplasm. Modulates the expression from both cellular and viral promoters. Down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin-beta. Also stimulates activation of human T-cell leukemia virus type I (HTLV-I) LTR. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.

Aliases: MDFIC antibody, MyoD family inhibitor domain-containing protein antibody, I-mfa domain-containing protein antibody, hIC antibody

UniProt: Q9P1T7