MDFIC Antikörper (Middle Region)

Produktnummer ABIN928479

Produktdetails anti-MDFIC Antikörper

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Bindungsspezifität: Middle Region

Reaktivität: Human, Kaninchen, Schwein, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFIC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Kaninchen, Schwein, Rind (Kuh)

Aufreinigung: Purified

Immunogen: MDFIC antibody was raised in rabbit using the middle region of MDFIC as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

MDFIC Blocking Peptide, catalog no. 33R-7305, is also available for use as a blocking control in assays to test for specificity of this MDFIC antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu MDFIC

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Andere Bezeichnung: MDFIC (MDFIC Produkte)

Synonyme: HIC antikoerper, Kdt1 antikoerper, Mdfid antikoerper, MyoD family inhibitor domain containing antikoerper, MyoD family inhibitor domain containing S homeolog antikoerper, MDFIC antikoerper, Mdfic antikoerper, mdfic.S antikoerper

Hintergrund: MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Synonyms: Polyclonal MDFIC antibody, Anti-MDFIC antibody, MyoD family inhibitor domain containing antibody, HIC antibody.