MDFIC Antikörper (N-Term)

Produktnummer ABIN2784369

Der Kaninchen Polyklonal anti-MDFIC Antikörper wird verwendet zum Nachweis von MDFIC in Proben von Human und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für MDFIC Antikörper (N-Term) (ABIN2784369)

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFIC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MDFIC Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MDFIC Antibody - N-terminal region

Sequenz: SVRPAGRRAR RQRRGAGSAE RPMSGAGEAL APGPVGPQRV AEAGGGQLGS

Homologie: Human: 100%, Rabbit: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MDFIC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MDFIC

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50877-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MDFIC

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Andere Bezeichnung: MDFIC

Hintergrund:

Background Information: MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.

Gene Name: MyoD family inhibitor domain containing

Alternative Symbols: HIC, MDFIC1

Protein Name: MyoD family inhibitor domain-containing protein

Molekulargewicht: 37kDa

Gen-ID: 29969

NCBI Accession: NP_951038

UniProt: Q9P1T7