APC2 Antikörper (Middle Region)

Produktnummer ABIN2784219

Dieses Anti-APC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von APC2 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für APC2 Antikörper (Middle Region) (ABIN2784219)

Target: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-APC2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LAVARIDQLV EDISALHTSS DDSFSLSSGD PGQEAPREGR AQSCSPCRGP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against APC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2303 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu APC2

Target: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Andere Bezeichnung: APC2

Hintergrund: APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.
Alias Symbols: APCL
Protein Interaction Partner: CTNNB1, NFX1, UBC, CDC27, ANAPC4, ANAPC10, CDC16, CDC23, ANAPC11, ANAPC7, ANAPC5, CDC26, CDH1, ANAPC1, MAPRE3, MAPRE1, Axin1, AXIN2, ACTA1,
Protein Size: 2303

Molekulargewicht: 244 kDa

Gen-ID: 10297

NCBI Accession: NM_005883, NP_005874

UniProt: Q9UJX6

Pathways: WNT Signalweg