APC2 Antikörper (Middle Region)

Produktnummer ABIN2784219

Dieser Anti-APC2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von APC2 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für APC2 Antikörper (Middle Region) (ABIN2784219)

Target: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-APC2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LAVARIDQLV EDISALHTSS DDSFSLSSGD PGQEAPREGR AQSCSPCRGP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against APC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2303 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu APC2

Target: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Andere Bezeichnung: APC2

Hintergrund: APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.
Alias Symbols: APCL
Protein Interaction Partner: CTNNB1, NFX1, UBC, CDC27, ANAPC4, ANAPC10, CDC16, CDC23, ANAPC11, ANAPC7, ANAPC5, CDC26, CDH1, ANAPC1, MAPRE3, MAPRE1, Axin1, AXIN2, ACTA1,
Protein Size: 2303

Molekulargewicht: 244 kDa

Gen-ID: 10297

NCBI Accession: NM_005883, NP_005874

UniProt: Q9UJX6

Pathways: WNT Signalweg