ING2 Antikörper (N-Term)

Produktnummer ABIN2784201

Dieses Anti-ING2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ING2 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für ING2 Antikörper (N-Term) (ABIN2784201)

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ING2 Antikörper

Bindungsspezifität: N-Term

Sequenz: TCYVQDYLEC VESLPHDMQR NVSVLRELDN KYQETLKEID DVYEKYKKED

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ING2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ING2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 280 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ING2

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Andere Bezeichnung: ING2

Hintergrund: This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.
Alias Symbols: ING1L, p33ING2
Protein Interaction Partner: SIRT1, WDR5, PRMT5, HIST3H3, UBC, HDAC1, APP, SMURF1, SUMO1, COPS2, TP53, SKIL, SMAD2, EP300, PCNA, HIST2H4A, SMURF2, SMAD1, HHT2, SAP30, HHT1, SIN3A, BRMS1L, SAP130, SUDS3, ARID4B, SMARCC2, SMARCC1, SMARCB1, RBBP7, RBBP4, ARID4A, HDAC2, ACTL6A,
Protein Size: 280

Molekulargewicht: 33 kDa

Gen-ID: 3622

NCBI Accession: NM_001564, NP_001555

UniProt: Q9H160

Pathways: Chromatin Binding, Autophagie, Negative Regulation of intrinsic apoptotic Signaling