GMP Synthase Antikörper (Middle Region)

Produktnummer ABIN2783438

Der Kaninchen Polyklonal anti-GMP Synthase Antikörper wird verwendet zum Nachweis von GMP Synthase in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für GMP Synthase Antikörper (Middle Region) (ABIN2783438)

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GMP Synthase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GMP Synthase Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: GMPS Antibody - middle region

Sequenz: VCTALLNRAL NQEQVIAVHI DNGFMRKRES QSVEEALKKL GIQVKVINAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GMPS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GMPS

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48619-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GMP Synthase

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Andere Bezeichnung: GMPS

Hintergrund:

Background Information: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

Gene Name: Guanine monphosphate synthetase

Alternative Symbols: GATD7

Protein Name: GMP synthase [glutamine-hydrolyzing]

Molekulargewicht: 77kDa

Gen-ID: 8833

NCBI Accession: NP_003866

UniProt: P49915

Pathways: Ribonucleoside Biosynthetic Process