MAPT Antikörper (Middle Region)
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- Target Alle MAPT Antikörper anzeigen
- MAPT (Microtubule-Associated Protein tau (MAPT))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAPT Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- RGAAPPGQKG QANATRIPAK TPPAPKTPPS SGEPPKSGDR SGYSSPGSPG
- Homologie
- Human: 100%, Mouse: 86%, Pig: 79%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MAPT. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MAPT
- Top Product
- Discover our top product MAPT Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 441 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MAPT (Microtubule-Associated Protein tau (MAPT))
- Andere Bezeichnung
- MAPT (MAPT Produkte)
- Synonyme
- DDPAC antikoerper, FTDP-17 antikoerper, MAPTL antikoerper, MSTD antikoerper, MTBT1 antikoerper, MTBT2 antikoerper, PPND antikoerper, TAU antikoerper, AI413597 antikoerper, AW045860 antikoerper, Mtapt antikoerper, Tau antikoerper, RNPTAU antikoerper, pTau antikoerper, tau antikoerper, xtp antikoerper, MAPT antikoerper, PHF-tau antikoerper, slc6a6 antikoerper, taut antikoerper, wu:fc26e12 antikoerper, microtubule associated protein tau antikoerper, microtubule-associated protein tau antikoerper, microtubule associated protein tau S homeolog antikoerper, Microtubule-associated protein tau antikoerper, solute carrier family 6 (neurotransmitter transporter), member 6b antikoerper, MAPT antikoerper, Mapt antikoerper, mapt.S antikoerper, LOC5580230 antikoerper, CpipJ_CPIJ013260 antikoerper, tau antikoerper, slc6a6b antikoerper
- Hintergrund
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MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Alias Symbols: DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Protein Interaction Partner: Ywhaz, Prkaca, STUB1, PHGK, SRC, PRKAR1A, GSK3B, FYN, DCTN1, CSNK1A1, CDK2, AKT1, ABL1, YWHAQ, SGK1, MARK2, MARCH7, TUBB3, TUBA1B, UBC, TUBA4A, MARK4, PEG10, MARK3, MARK1, MAPK13, MAPK11, MAPK8, mapk14, Mapk12, LIMS1, HSPA1A, PPP5C, PPP2R4, CAPN2, PKN1, H
Protein Size: 441 - Molekulargewicht
- 46 kDa
- Gen-ID
- 4137
- NCBI Accession
- NM_005910, NP_005901
- Pathways
- MAPK Signalweg, Microtubule Dynamics, M Phase, Regulation of Cell Size
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