EDEM1 Antikörper (N-Term)

Produktnummer ABIN2782826

Der Kaninchen Polyklonal Anti-EDEM1 Antikörper wurde für WB validiert. Er ist geeignet, EDEM1 in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Hund und Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für EDEM1 Antikörper (N-Term) (ABIN2782826)

Target: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Hund, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDEM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EDEM1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MAHAFPQDEL NPIHCRGRGP DRGDPSNLNI NDVLGNYSLT LVDALDTLAI

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against EDEM1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EDEM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 657 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EDEM1

Target: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Andere Bezeichnung: EDEM1

Hintergrund: EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
Alias Symbols: EDEM, KIAA0212
Protein Interaction Partner: HLA-B, SQSTM1, UBC, MMS19, SSR1, ASGR1, DERL1, DNAJC10, DERL2, SEC61B, SEL1L, RHO, CANX, RCOM_2159910, ASGR2, ELAVL1, BZW1,
Protein Size: 657

Molekulargewicht: 74 kDa

Gen-ID: 9695

NCBI Accession: NM_014674, NP_055489

UniProt: Q92611

Pathways: ER-Nucleus Signaling