Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRAM2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd, Kaninchen, Hund, Meerschweinchen, Rind (Kuh) und Zebrafisch (Danio rerio).
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
TRAM2
(Translocation Associated Membrane Protein 2 (TRAM2))
Andere Bezeichnung
Tram2
Hintergrund
Tram2 is necessary for collagen type I synthesis. It may couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding. Alias Symbols: C330003D03Rik Protein Size: 370