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ALDH6A1 Antikörper (Middle Region)

Der Kaninchen Polyklonal Anti-ALDH6A1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ALDH6A1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2782682

Kurzübersicht für ALDH6A1 Antikörper (Middle Region) (ABIN2782682)

Target

Alle ALDH6A1 Antikörper anzeigen
ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Reaktivität

  • 59
  • 9
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt

  • 45
  • 11
  • 3
Kaninchen

Klonalität

  • 50
  • 9
Polyklonal

Konjugat

  • 33
  • 5
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ALDH6A1 Antikörper ist unkonjugiert

Applikation

  • 47
  • 35
  • 31
  • 12
  • 9
  • 6
  • 5
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    GQVGVNVPIP VPLPMFSFTG SRSSFRGDTN FYGKQGIQFY TQLKTITSQW

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ALDH6A1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human ALDH6A1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 535 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kuiper, Williams, Distl, Drögemüller: "Assignment of the PAX6 gene to bovine chromosome 15q25-->q27 by fluorescence in situ hybridization and confirmation by radiation hybrid mapping." in: Cytogenetic and genome research, Vol. 109, Issue 4, pp. 533, (2005) (PubMed).

  • Target

    ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

    Andere Bezeichnung

    ALDH6A1

    Hintergrund

    ALDH6A1 plays a role in valine and pyrimidine metabolism. ALDH6A1 binds fatty acyl-CoA. This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
    Alias Symbols: MGC40271, MMSADHA, MMSDH
    Protein Interaction Partner: UBC, LMO2,
    Protein Size: 535

    Molekulargewicht

    58 kDa

    Gen-ID

    4329

    NCBI Accession

    NM_005589, NP_005580

    UniProt

    Q02252

    Pathways

    Brown Fat Cell Differentiation
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