UBD Antikörper (N-Term)

Produktnummer ABIN2782518

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UBD in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen und Schwein.

Kurzübersicht für UBD Antikörper (N-Term) (ABIN2782518)

Target: UBD (Ubiquitin D (UBD))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UBD Antikörper

Bindungsspezifität: N-Term

Sequenz: RSKTKVPVQD QVLLLGSKIL KPRRSLSSYG IDKEKTIHLT LKVVKPSDEE

Homologie: Cow: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 85%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against UBD. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 165 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBD

Target: UBD (Ubiquitin D (UBD))

Andere Bezeichnung: UBD

Hintergrund: UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is not significantly overexpressed in cancers lacking a proinflammatory environment. Immunohistochemical studies demonstrated increased UBD expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.
Alias Symbols: FAT10, UBD-3, GABBR1
Protein Interaction Partner: UBE2Z, SRPK2, SRPK1, RPLP0, RPL27A, RPL23A, RPL12, RPL11, SNORA62, RBBP4, RANBP2, QARS, PSMD2, PRKDC, PRKCSH, PPIB, PPIA, PLEC, PGK1, PCNA, PCBP1, P4HB, NSUN2, TRIM28, PDIA6, ABCF2, SMC4, PDCD6IP, NPEPPS, EFTUD2, PAPSS2, HIP1R, SNORD73A, IQGAP1, PABPC4, E
Protein Size: 165

Molekulargewicht: 18 kDa

Gen-ID: 10537

NCBI Accession: NM_006398, NP_006389

UniProt: O15205

Pathways: Ubiquitin Proteasome Pathway