ESRRA Antikörper (N-Term)

Produktnummer ABIN2782281

Produktdetails anti-ESRRA Antikörper

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KEGVRLDRVR GGRQKYKRRP EVDPLPFPGP FPAGPLAVAG GPRKTAAPVN

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ESRRA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ESRRA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 423 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: ESRRA (ESRRA Produkte)

Synonyme: err1 antikoerper, erra antikoerper, esrral antikoerper, erralpha antikoerper, nr3b1 antikoerper, MGC80854 antikoerper, ESRRA antikoerper, esrl1 antikoerper, LOC100125507 antikoerper, ERRalpha antikoerper, Err1 antikoerper, Estrra antikoerper, Nr3b1 antikoerper, Errra antikoerper, ERR1 antikoerper, ERRa antikoerper, ESRL1 antikoerper, NR3B1 antikoerper, ESTRRA antikoerper, estrogen-related receptor alpha antikoerper, estrogen related receptor alpha L homeolog antikoerper, estrogen related receptor alpha antikoerper, catsper channel auxiliary subunit zeta antikoerper, estrogen related receptor, alpha antikoerper, esrra antikoerper, esrra.L antikoerper, ESRRA antikoerper, LOC100125507 antikoerper, CATSPERZ antikoerper, Esrra antikoerper

Hintergrund: ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERR1, ERRa, ERRalpha, ESRL1, NR3B1
Protein Interaction Partner: SUMO2, SUMO3, NSD1, NCOA1, EXOSC6, SMARCD3, ESR1, PIAS4, NXF1, ATXN1, MAP2K5, FUS, ADH5, WDR36, ZNF606, C2CD5, IPO13, TFAP4, Cebpb, ESRRG, PPARGC1A, MACF1, EIF3I, NR0B2, NRIP1, NCOA3, TNNI2, SRC, PROX1, DUT, NR0B1, UBC, PARK2, ZNF658B, SPICE1, KDM3B, DPF1
Protein Size: 423

Molekulargewicht: 46 kDa

Gen-ID: 2101

NCBI Accession: NM_004451, NP_004442

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha