ESRRA Antikörper (N-Term)

Produktnummer ABIN2782281

Dieses Anti-ESRRA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ESRRA in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für ESRRA Antikörper (N-Term) (ABIN2782281)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ESRRA Antikörper

Bindungsspezifität: N-Term

Sequenz: KEGVRLDRVR GGRQKYKRRP EVDPLPFPGP FPAGPLAVAG GPRKTAAPVN

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ESRRA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ESRRA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 423 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: ESRRA

Hintergrund: ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERR1, ERRa, ERRalpha, ESRL1, NR3B1
Protein Interaction Partner: SUMO2, SUMO3, NSD1, NCOA1, EXOSC6, SMARCD3, ESR1, PIAS4, NXF1, ATXN1, MAP2K5, FUS, ADH5, WDR36, ZNF606, C2CD5, IPO13, TFAP4, Cebpb, ESRRG, PPARGC1A, MACF1, EIF3I, NR0B2, NRIP1, NCOA3, TNNI2, SRC, PROX1, DUT, NR0B1, UBC, PARK2, ZNF658B, SPICE1, KDM3B, DPF1
Protein Size: 423

Molekulargewicht: 46 kDa

Gen-ID: 2101

NCBI Accession: NM_004451, NP_004442

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha