Indian Hedgehog Antikörper (N-Term)

Produktnummer ABIN2782160

Dieses Anti-Indian Hedgehog-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Indian Hedgehog in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Indian Hedgehog Antikörper (N-Term) (ABIN2782160)

Target: Indian Hedgehog (IHH)

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Indian Hedgehog Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Indian Hedgehog Antikörper

Bindungsspezifität: N-Term

Sequenz: AAWGCGPGRV VGSRRRPPRK LVPLAYKQFS PNVPEKTLGA SGRYEGKIAR

Homologie: Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IHH. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IHH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 411 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Indian Hedgehog Antikörper (ABIN2782160)

Mirza, Qiao, Tateyama, Miyamoto, Xiuli, Seo: "3?-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species." in: Journal of bone and mineral metabolism, Vol. 30, Issue 2, pp. 144-53, (2012) (PubMed).

Details zu Indian Hedgehog

Target: Indian Hedgehog (IHH)

Andere Bezeichnung: IHH

Hintergrund: IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP).
Alias Symbols: BDA1, HHG2
Protein Interaction Partner: RHOD, HHIP, PTCH2, PTCH1,
Protein Size: 411

Molekulargewicht: 45 kDa

Gen-ID: 3549

NCBI Accession: NM_002181, NP_002172

UniProt: Q14623

Pathways: Hedgehog Signalweg