SPPL2B Antikörper (N-Term)

Produktnummer ABIN2782089

Produktdetails anti-SPPL2B Antikörper

Target: SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Rind (Kuh), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPPL2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AHLPHDLSKA SFLQLRNWTA SLLCSAADLP ARGFSNQIPL VARGNCTFYE

Homologie: Cow: 79%, Horse: 86%, Human: 100%, Pig: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SPPL2B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPPL2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SPPL2B

Target: SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

Andere Bezeichnung: SPPL2B (SPPL2B Produkte)

Hintergrund: SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
Alias Symbols: IMP-4, IMP4, PSH4, PSL1
Protein Size: 307

Molekulargewicht: 33 kDa

Gen-ID: 56928

NCBI Accession: NM_152988, NP_694533