CISD2 Antikörper (N-Term)
Kurzübersicht für CISD2 Antikörper (N-Term) (ABIN2781919)
Target
Alle CISD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- VLESVARIVK VQLPAYLKRL PVPESITGFA RLTVSEWLRL LPFLGVLALL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CISD2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CISD2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 135 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
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Andere Bezeichnung
- CISD2
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Hintergrund
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CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. It binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2 (WFS2).
Alias Symbols: ERIS, Miner1, WFS2, ZCD2, NAF-1
Protein Interaction Partner: UBC, LMNA, APP, SPP1, BCL2, ELAVL1,
Protein Size: 135 -
Molekulargewicht
- 15 kDa
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Gen-ID
- 493856
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NCBI Accession
- NM_001008388, NP_001008389
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UniProt
- Q8N5K1
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Pathways
- Activation of Innate immune Response
Target
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