SLC39A4 Antikörper (N-Term)

Produktnummer ABIN405621

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-SLC39A4 Antikörper (ABIN405621) detektiert spezifisch SLC39A4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Kaninchen und Rind (Kuh).

Kurzübersicht für SLC39A4 Antikörper (N-Term) (ABIN405621)

Target: SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))

Reaktivität: Human, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SLC39A4 Antikörper

Bindungsspezifität: N-Term

Sequenz: ASLVSLELGL LLAVLVVTAT ASPPAGLLSL LTSGQGALDQ EALGGLLNTL

Homologie: Cow: 86%, Human: 100%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC39A4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC39A4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 647 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC39A4 Antikörper (ABIN405621)

Antala, Ovchinnikov, Kamisetty, Baker, Dempski: "Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17796-805, (2015) (PubMed).

Details zu SLC39A4

Target: SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))

Andere Bezeichnung: SLC39A4

Hintergrund: SLC39A4 is a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in the gene encoding SLC39A4 result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc.This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AEZ, FLJ20327, MGC74741, ZIP4, AWMS2
Protein Interaction Partner: UBC,
Protein Size: 647

Molekulargewicht: 68 kDa

Gen-ID: 55630

NCBI Accession: NM_130849, NP_570901

UniProt: Q6P5W5

Pathways: Transition Metal Ion Homeostasis, Autophagie