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PAM Antikörper (C-Term)

PAM Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781312
  • Target Alle PAM Antikörper anzeigen
    PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 22
    • 10
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund, Zebrafisch (Danio rerio)
    Wirt
    • 18
    • 3
    • 1
    Kaninchen
    Klonalität
    • 21
    • 1
    Polyklonal
    Konjugat
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PAM Antikörper ist unkonjugiert
    Applikation
    • 11
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GLNLGNFFAS RKGYSRKGFD RLSTEGSDQE KEDDGSESEE EYSAPLPALA
    Homologie
    Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 93%, Zebrafish: 75%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PAM. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of human PAM
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
    Andere Bezeichnung
    PAM (PAM Produkte)
    Synonyme
    PAL antikoerper, PHM antikoerper, pal antikoerper, phm antikoerper, pamb antikoerper, CG3832 antikoerper, Dmel\\CG3832 antikoerper, dPHM antikoerper, AE-I antikoerper, PAL-A antikoerper, PHM-A antikoerper, pama antikoerper, si:dkeyp-35f12.2 antikoerper, peptidylglycine alpha-amidating monooxygenase antikoerper, peptidylglycine alpha-amidating monooxygenase S homeolog antikoerper, Peptidylglycine-alpha-hydroxylating monooxygenase antikoerper, peptidylglycine alpha-amidating monooxygenase L homeolog antikoerper, PAM antikoerper, Pam antikoerper, pam.S antikoerper, CHLREDRAFT_150435 antikoerper, sce7070 antikoerper, pam antikoerper, Phm antikoerper, pam.L antikoerper
    Hintergrund
    This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    Alias Symbols: PAL, PHM
    Protein Size: 335
    Molekulargewicht
    36 kDa
    Gen-ID
    5066
    NCBI Accession
    NM_000919, NP_000910
    UniProt
    P19021
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