PAM Antikörper (Internal Region)

Produktnummer ABIN6264025

Produktdetails anti-PAM Antikörper

Target: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: PAM Antibody detects endogenous levels of total PAM.

Homologie: Pig,Horse,Sheep

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PAM, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PAM

Target: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Andere Bezeichnung: PAM (PAM Produkte)

Synonyme: PAL antikoerper, PHM antikoerper, pal antikoerper, phm antikoerper, pamb antikoerper, CG3832 antikoerper, Dmel\\CG3832 antikoerper, dPHM antikoerper, AE-I antikoerper, PAL-A antikoerper, PHM-A antikoerper, pama antikoerper, si:dkeyp-35f12.2 antikoerper, peptidylglycine alpha-amidating monooxygenase antikoerper, peptidylglycine alpha-amidating monooxygenase S homeolog antikoerper, Peptidylglycine-alpha-hydroxylating monooxygenase antikoerper, peptidylglycine alpha-amidating monooxygenase L homeolog antikoerper, PAM antikoerper, Pam antikoerper, pam.S antikoerper, CHLREDRAFT_150435 antikoerper, sce7070 antikoerper, pam antikoerper, Phm antikoerper, pam.L antikoerper

Hintergrund:

Description: Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.

Gene: PAM

Molekulargewicht: 108 kDa

Gen-ID: 5066

UniProt: P19021