TFEB Antikörper (C-Term)

Produktnummer ABIN183717

Der Kaninchen Polyklonal anti-TFEB Antikörper (ABIN183717) detektiert spezifisch TFEB in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Ziege, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Schaf und Zebrafisch (Danio rerio).

Kurzübersicht für TFEB Antikörper (C-Term) (ABIN183717)

Target: TFEB (Transcription Factor EB (TFEB))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Ziege, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFEB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TFEB Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TFEB Antibody - C-terminal region

Sequenz: SLSKKDLDLM LLDDSLLPLA SDPLLSTMSP EASKASSRRS SFSMEEGDVL

Homologie: Cow: 100%, Dog: 100%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Yeast: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against TFEB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TFEB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38810-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TFEB

Target: TFEB (Transcription Factor EB (TFEB))

Andere Bezeichnung: TFEB

Hintergrund:

Background Information: TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t(6,11)(p21,q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.

Gene Name: Transcription factor EB

Alternative Symbols: TCFEB, BHLHE35, ALPHATFEB

Protein Name: Transcription factor EB

Molekulargewicht: 53kDa

Gen-ID: 7942

NCBI Accession: NP_009093

UniProt: P19484