FOXA1 Antikörper (N-Term)

Produktnummer ABIN2780597

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXA1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Hund, Rind (Kuh), Schwein, Zebrafisch (Danio rerio), Meerschweinchen und Kaninchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für FOXA1 Antikörper (N-Term) (ABIN2780597)

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Schwein, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FOXA1 Antikörper

Bindungsspezifität: N-Term

Sequenz: LGTVKMEGHE TSDWNSYYAD TQEAYSSVPV SNMNSGLGSM NSMNTYMTMN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 85%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 85%, Rat: 93%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 472 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOXA1 Antikörper (ABIN2780597)

Menga, Infantino, Iacobazzi, Convertini, Palmieri, Iacobazzi: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).

Details zu FOXA1

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Andere Bezeichnung: FOXA1

Hintergrund: FOXA1 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HNF3A, MGC33105, TCF3A
Protein Interaction Partner: EED, SEZ6L2, AHR, ELAVL1, SUMO2, TLE1, HDAC7, HIST3H3, AR, ONECUT1, DSCAM, NRIP1, XBP1, TFF1,
Protein Size: 472

Molekulargewicht: 49 kDa

Gen-ID: 3169

NCBI Accession: NM_004496, NP_004487

UniProt: P55317

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis