EED Antikörper (N-Term)

Produktnummer ABIN2780548

Produktdetails anti-EED Antikörper

Target: EED (Embryonic Ectoderm Development (EED))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EED Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QKLSSDENSN PDLSGDENDD AVSIESGTNT ERPDTPTNTP NAPGRKSWGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EED. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EED

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 400 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EED

Target: EED (Embryonic Ectoderm Development (EED))

Andere Bezeichnung: EED (EED Produkte)

Synonyme: Xeed antikoerper, heed antikoerper, wait1 antikoerper, EED antikoerper, HEED antikoerper, WAIT1 antikoerper, zgc:112509 antikoerper, Xeed-B antikoerper, eed antikoerper, psXEED antikoerper, ENSMUSG00000039373 antikoerper, l(7)5Rn antikoerper, l7Rn5 antikoerper, lusk antikoerper, Xeed-A antikoerper, embryonic ectoderm development antikoerper, embryonic ectoderm development S homeolog antikoerper, microRNA 6755 antikoerper, embryonic ectoderm development L homeolog antikoerper, eed antikoerper, EED antikoerper, eed.S antikoerper, MIR6755 antikoerper, Eed antikoerper, eed.L antikoerper

Hintergrund: EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function.
Alias Symbols: HEED, WAIT1
Protein Interaction Partner: PINK1, BRCA1, ADAM17, EZH2, IMP3, PSPC1, NAT10, PBRM1, RIF1, RBM28, HEATR1, MAGOHB, ARGLU1, MRPL20, NRDE2, CASZ1, BCOR, EXOSC4, LUC7L3, SF3B6, NOP58, SRRT, RAB14, C9orf114, CRNKL1, DDX47, HP1BP3, MYEF2, TRA2A, CPSF1, IGHV3-23, UTP20, PRPF19, ZNF638, RBMX,
Protein Size: 400

Molekulargewicht: 45 kDa

Gen-ID: 8726

NCBI Accession: NM_152991, NP_694536