NME1 Antikörper (C-Term)

Produktnummer ABIN2780437

Produktdetails anti-NME1 Antikörper

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NME1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Dot Blot (DB)

Sequenz: NVVKTGRVML GETNPADSKP GTIRGDFCIQ VGRNIIHGSD SVKSAEKEIS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against Nme1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 152 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NME1

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Andere Bezeichnung: Nme1 (NME1 Produkte)

Hintergrund: Nme1 has a major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. It possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. It is involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Itis required for neural development including neural patterning and cell fate determination.
Alias Symbols: AL024257, NDPK-A, NM23-M1, NM23A
Protein Interaction Partner: Plcb1, Rara,
Protein Size: 152

Molekulargewicht: 17 kDa

Gen-ID: 18102

NCBI Accession: NM_008704, NP_032730

UniProt: P15532

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process