NEUROD1 Antikörper (Middle Region)

Produktnummer ABIN2780434

Dieses Anti-NEUROD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NEUROD1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Schwein, Schaf und Zebrafisch (Danio rerio).

Kurzübersicht für NEUROD1 Antikörper (Middle Region) (ABIN2780434)

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Schwein, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEUROD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NEUROD1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: ATLAGAQSHG SIFSGTAAPR CEIPIDNIMS FDSHSHHERV MSAQLNAIFH

Homologie: Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NEUROD1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NEUROD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 356 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Andere Bezeichnung: NEUROD1

Hintergrund: NeuroD1is a members of bHLH family that involves in neuroendocrine differentiation. This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BETA2, BHF-1, NEUROD, MODY6, bHLHa3
Protein Interaction Partner: DUSP3, SMARCA4, MAFA, EP300, TCF4, RREB1, PITX1, NEUROD1, HAP1, PDX1, CALM3, CALM1, CCND1, MAP3K10, HTT,
Protein Size: 356

Molekulargewicht: 40 kDa

Gen-ID: 4760

NCBI Accession: NM_002500, NP_002491

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis