Glutamate Receptor 1 Antikörper (N-Term)

Produktnummer ABIN2780202

Der Kaninchen Polyklonal Anti-Glutamate Receptor 1-Antikörper wurde für WB validiert. Er ist geeignet, Glutamate Receptor 1 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für Glutamate Receptor 1 Antikörper (N-Term) (ABIN2780202)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: N-Term

Sequenz: CGALHVCFIT PSFPVDTSNQ FVLQLRPELQ EALISIIDHY KWQTFVYIYD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against Gria1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 907 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: Gria1

Hintergrund: Gria1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Alias Symbols: 2900051M01Rik, AI853806, Glr-1, Glr1, GluR-A, GluRA, Glur-1, Glur1, HIPA1, GluA1, gluR-K1
Protein Interaction Partner: Lrp1, Grin2c, Grin2a, Grin1, Gria2, Eps8, Cacng2, Sqstm1, HOMER2,
Protein Size: 907

Molekulargewicht: 102 kDa

Gen-ID: 14799

NCBI Accession: NM_001113325, NP_001106796

UniProt: P23818

Pathways: PI3K-Akt Signalweg