MEF2C Antikörper (N-Term)

Produktnummer ABIN2780048

Dieser Anti-MEF2C Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MEF2C in WB. Geeignet für Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen und Rind (Kuh). Dieses Primary Antibody wurde in 6+ Publikationen zitiert.

Kurzübersicht für MEF2C Antikörper (N-Term) (ABIN2780048)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEF2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MEF2C Antikörper

Bindungsspezifität: N-Term

Sequenz: SRTNSDIVEA LNKKENKGSE SPDPDSSYAL TPRTEEKYKK INEEFDNMIK

Homologie: Cow: 86%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MEF2C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse MEF2C

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 432 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MEF2C Antikörper (ABIN2780048)

Law, Leung, Yau, Tse, Wong, Leung, Mascheck, Huang, Sauer, Tsang et al.: "Regulation of multiple transcription factors by reactive oxygen species and effects of pro-inflammatory cytokines released during myocardial infarction on cardiac differentiation of embryonic stem ..." in: International journal of cardiology, Vol. 168, Issue 4, pp. 3458-72, (2013) (PubMed).

Inagawa, Miyamoto, Yamakawa, Muraoka, Sadahiro, Umei, Wada, Katsumata, Kaneda, Nakade, Kurihara, Obata, Miyake, Fukuda, Ieda: "Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5." in: Circulation research, Vol. 111, Issue 9, pp. 1147-56, (2012) (PubMed).

Escher, Schorderet, Cottet: "Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice." in: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5933-40, (2011) (PubMed).

Blin, Nury, Stefanovic, Neri, Guillevic, Brinon, Bellamy, Rücker-Martin, Barbry, Bel, Bruneval, Cowan, Pouly, Mitalipov, Gouadon, Binder, Hagège, Desnos, Renaud, Menasché, Pucéat: "A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates." in: The Journal of clinical investigation, Vol. 120, Issue 4, pp. 1125-39, (2010) (PubMed).

Lombardi, Dong, Rodriguez, Bell, Leung, Schwartz, Willerson, Brugada, Marian: "Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy." in: Circulation research, Vol. 104, Issue 9, pp. 1076-84, (2009) (PubMed).

Leschik, Stefanovic, Brinon, Pucéat: "Cardiac commitment of primate embryonic stem cells." in: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, (2008) (PubMed).

Details zu MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Andere Bezeichnung: MEF2C

Hintergrund: MEF2C is a transcription regulator of slow fiber
Alias Symbols: Mef2, AV011172, 5430401D19Rik, 9930028G15Rik
Protein Interaction Partner: Vgll2, Hdac4, Nkx2-5, Hdac5, Phb2, KDM1A, Carm1, Ifrd1, Ncoa3, Ncoa2, Foxh1,
Protein Size: 432

Molekulargewicht: 48 kDa

Gen-ID: 17260

NCBI Accession: NM_025282, NP_079558

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling