HNF4A Antikörper (Middle Region)

Produktnummer ABIN2779763

Dieser Anti-HNF4A-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von HNF4A in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Pferd, Kaninchen, Meerschweinchen, Schaf und Zebrafisch (Danio rerio).

Kurzübersicht für HNF4A Antikörper (Middle Region) (ABIN2779763)

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Pferd, Kaninchen, Meerschweinchen, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HNF4A Antikörper

Bindungsspezifität: Middle Region

Sequenz: RGQAATPETP QPSPPGGSGS EPYKLLPGAV ATIVKPLSAI PQPTITKQEV

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%, Zebrafish: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against HNF4A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HNF4A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 452 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HNF4A

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Andere Bezeichnung: HNF4A

Hintergrund: The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression
Alias Symbols: FLJ39654, HNF4, HNF4a7, HNF4a8, HNF4a9, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14, HNF4alpha
Protein Interaction Partner: PIAS4, SUMO1, SUMO2, RNF4, SUB1, CREBBP, TBP, TAF9, TAF6, TADA2A, GTF2H1, GTF2B, ANP32B, MDM2, GPS2, PPARGC1A, HNF4A, NCOA6, SMAD4, SMAD3, PNRC2, COPS5, PNRC1, NR0B2, NRIP1, UBE2I, PROX1, NPPA, SREBF2, VDR, MAPK3, MAPK1, SIRT1, SREBF1, XPO1, SP1, HDAC3, T
Protein Size: 452

Molekulargewicht: 50 kDa

Gen-ID: 3172

NCBI Accession: NM_175914, NP_787110

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process