HNF4A Antikörper (AA 200-300)

Produktnummer ABIN3022870

Produktdetails anti-HNF4A Antikörper

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Bindungsspezifität: AA 200-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EWAKYIPAFC ELPLDDQVAL LRAHAGEHLL LGATKRSMVF KDVLLLGNDY IVPRHCPELA EMSRVSIRIL DELVLPFQEL QIDDNEYAYL KAIIFFDPDA K

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human HNF4A (NP_000448.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-HNF4A Antikörper (ABIN3022870)

Wei, Dai, Zhou, He, Yao, Zhao, Guo, Yang: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).

Details zu HNF4A

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Andere Bezeichnung: HNF4A (HNF4A Produkte)

Synonyme: HNF4A antikoerper, HNF4alpha antikoerper, CG9310 antikoerper, DmHNF4 antikoerper, Dmel\\CG9310 antikoerper, HNF-4 antikoerper, HNF-4(D) antikoerper, HNF4 antikoerper, Hnf-4 antikoerper, Hnf-4h antikoerper, NR2A4 antikoerper, dHNF-4 antikoerper, dHNF4 antikoerper, Hnf4 antikoerper, Hnf4alpha antikoerper, MODY1 antikoerper, Nr2a1 antikoerper, Tcf14 antikoerper, HNF4a7 antikoerper, HNF4a8 antikoerper, HNF4a9 antikoerper, MODY antikoerper, NR2A1 antikoerper, NR2A21 antikoerper, TCF antikoerper, TCF14 antikoerper, HNF-4alpha antikoerper, fb58h09 antikoerper, id:ibd1279 antikoerper, wu:fb58h09 antikoerper, hnf4 antikoerper, nr2a1 antikoerper, hepatocyte nuclear factor 4 alpha antikoerper, Hepatocyte nuclear factor 4 antikoerper, hepatic nuclear factor 4, alpha antikoerper, hepatocyte nuclear factor 4, alpha antikoerper, hepatocyte nuclear factor 4 alpha S homeolog antikoerper, HNF4A antikoerper, hnf4a antikoerper, Hnf4 antikoerper, Hnf4a antikoerper, hnf4a.S antikoerper

Hintergrund: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.,HNF4A,FRTS4,HNF4,HNF4a7,HNF4a8,HNF4a9,HNF4alpha,MODY,MODY1,NR2A1,NR2A21,TCF,TCF14,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cytochromes,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Stem Cells,Cardiovascular,Blood,Coagulation,Lipids,HNF4A

Molekulargewicht: 43-56 kDa

Gen-ID: 3172

UniProt: P41235

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process