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WWTR1 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-WWTR1-Antikörper wurde für WB validiert. Er ist geeignet, WWTR1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen und Kaninchen zu detektieren.
Produktnummer ABIN2779708

Kurzübersicht für WWTR1 Antikörper (N-Term) (ABIN2779708)

Target

Alle WWTR1 Antikörper anzeigen
WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

Reaktivität

Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt

  • 29
  • 5
Kaninchen

Klonalität

  • 29
  • 5
Polyklonal

Konjugat

  • 24
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser WWTR1 Antikörper ist unkonjugiert

Applikation

  • 27
  • 12
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    PRLAGGAQHV RSHSSPASLQ LGTGAGAAGS PAQQHAHLRQ QSYDVTDELP

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against WWTR1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human WWTR1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 400 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

    Andere Bezeichnung

    WWTR1

    Hintergrund

    TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
    Alias Symbols: DKFZP586I1419, TAZ
    Protein Interaction Partner: MED28, NOTCH1, YWHAQ, LATS1, BTRC, YWHAE, TP53BP2, PPP1CA, KLF5, YWHAZ, YWHAG, PAX3, SLC9A3R2, TEAD3, TEAD4, NKX2-1, RUNX1,
    Protein Size: 400

    Molekulargewicht

    44 kDa

    Gen-ID

    25937

    NCBI Accession

    NM_015472, NP_056287

    UniProt

    Q9GZV5

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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