NCOR1 Antikörper (N-Term)

Produktnummer ABIN2779671

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NCOR1 in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh) und Saccharomyces cerevisiae.

Kurzübersicht für NCOR1 Antikörper (N-Term) (ABIN2779671)

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-NCOR1 Antikörper

Bindungsspezifität: N-Term

Sequenz: NENYKALVRR NYGKRRGRNQ QIARPSQEEK VEEKEEDKAE KTEKKEEEKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 92%, Yeast: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against NCOR1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2453 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Andere Bezeichnung: NCOR1

Hintergrund: NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
Alias Symbols: N-CoR, TRAC1, N-CoR1, hN-CoR
Protein Interaction Partner: RARA, TP53, ESR1, PHB2, ZBTB16, THRB, THRA, CREB1, JUN, PPARG, SQSTM1, HDAC3, UBE2I, SOX2, HDAC7, HDAC5, HDAC4, UBC, SKIL, SKI, AR, SMAD4, CSNK2A1, RUNX1T1, CXADR, TBL1XR1, vif, C1D, CHUK, YWHAZ, SMARCE1, SMARCD1, SMARCA2, RBBP4, BPTF, HMGXB4, TAB2, NCOR2
Protein Size: 2453

Molekulargewicht: 270 kDa

Gen-ID: 9611

UniProt: Q60974

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process