NCOR1 Antikörper (N-Term)

Produktnummer ABIN2779671

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch NCOR1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh) und Saccharomyces cerevisiae.

Kurzübersicht für NCOR1 Antikörper (N-Term) (ABIN2779671)

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NCOR1 Antikörper

Bindungsspezifität: N-Term

Sequenz: NENYKALVRR NYGKRRGRNQ QIARPSQEEK VEEKEEDKAE KTEKKEEEKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 92%, Yeast: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against NCOR1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2453 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Andere Bezeichnung: NCOR1

Hintergrund: NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
Alias Symbols: N-CoR, TRAC1, N-CoR1, hN-CoR
Protein Interaction Partner: RARA, TP53, ESR1, PHB2, ZBTB16, THRB, THRA, CREB1, JUN, PPARG, SQSTM1, HDAC3, UBE2I, SOX2, HDAC7, HDAC5, HDAC4, UBC, SKIL, SKI, AR, SMAD4, CSNK2A1, RUNX1T1, CXADR, TBL1XR1, vif, C1D, CHUK, YWHAZ, SMARCE1, SMARCD1, SMARCA2, RBBP4, BPTF, HMGXB4, TAB2, NCOR2
Protein Size: 2453

Molekulargewicht: 270 kDa

Gen-ID: 9611

UniProt: Q60974

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process