POLR2B Antikörper (N-Term)
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- Target Alle POLR2B Antikörper anzeigen
- POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POLR2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- TYSAPLYVDI TKTVIKEGEE QLQTQHQKTF IGKIPIMLRS TYCLLNGLTD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against POLR2B. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human POLR2B
- Top Product
- Discover our top product POLR2B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1174 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
- Andere Bezeichnung
- POLR2B (POLR2B Produkte)
- Synonyme
- Pol2rb antikoerper, Rpb140 antikoerper, Rpb2 antikoerper, POL2RB antikoerper, RPB2 antikoerper, hRPB140 antikoerper, hsRPB2 antikoerper, RNA polymerase II subunit B antikoerper, polymerase (RNA) II (DNA directed) polypeptide B, 140kDa antikoerper, DNA-directed RNA polymerase II subunit RPB2 antikoerper, polymerase (RNA) II (DNA directed) polypeptide B antikoerper, polymerase (RNA) II (DNA directed) polypeptide B, 140kDa L homeolog antikoerper, POLR2B antikoerper, polr2b antikoerper, LOC100640211 antikoerper, Polr2b antikoerper, polr2b.L antikoerper, rpb-2 antikoerper
- Hintergrund
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POLR2B is the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
Alias Symbols: RPB2, POL2RB, hsRPB2, hRPB140
Protein Interaction Partner: ESR1, UBC, TCEB3, SRC, PSMB9, SUMO2, XRN2, WWOX, SUZ12, RNF2, NEDD4, ITCH, RABEP2, HECW2, FBXO6, CDK20, HDAC11, ILK, POLR2C, MED19, MED26, RECQL5, VCP, BARD1, MDC1, POLR3F, TUBB4B, TUBA4A, POLR2I, POLR2E, POLR2D, POLR2A, DCTN1, ATP6V1B2, MEN1, CDK7, CCNH,
Protein Size: 1174 - Molekulargewicht
- 134 kDa
- Gen-ID
- 5431
- NCBI Accession
- NM_000938, NP_000929
- UniProt
- P30876
- Pathways
- Regulatorische RNA Pathways, DNA Reparatur
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