TLE2 Antikörper (N-Term)

Produktnummer ABIN2779582

Der Kaninchen Polyklonal anti-TLE2 Antikörper wird verwendet zum Nachweis von TLE2 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für TLE2 Antikörper (N-Term) (ABIN2779582)

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TLE2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TLE2 Antibody - N-terminal region

Sequenz: VEEERPSGPG GGGKQRADEK EPSGPYESDE DKSDYNLVVD EDQPSEPPSP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TLE2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114226

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TLE2

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Andere Bezeichnung: TLE2

Hintergrund:

Background Information: TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.

Gene Name: Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)

Alternative Symbols: ESG, ESG2, GRG2

Protein Name: Transducin-like enhancer protein 2

Molekulargewicht: 80kDa

Gen-ID: 7089

NCBI Accession: NP_003251

UniProt: Q04725

Pathways: WNT Signalweg