TLE2 Antikörper (AA 180-260)

Produktnummer ABIN7224714

Der Kaninchen Polyklonal anti-TLE2 Antikörper wird verwendet zum Nachweis von TLE2 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für TLE2 Antikörper (AA 180-260) (ABIN7224714)

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TLE2 Antikörper

Bindungsspezifität: AA 180-260

Verwendungszweck: Rabbit Anti-TLE2 Polyclonal Antibody

Spezifität: TLE2 Polyclonal Antibody detects endogenous levels of TLE2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TLE2 at AA range: 180-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TLE2

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Andere Bezeichnung: TLE2

Hintergrund: TLE2, Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.

Molekulargewicht: 110kD

Gen-ID: 7089

UniProt: Q04725

Pathways: WNT Signalweg