ESRRA Antikörper (C-Term)

Produktnummer ABIN2779529

Produktdetails anti-ESRRA Antikörper

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AGRAGPGGGA ERRRAGRLLL TLPLLRQTAG KVLAHFYGVK LEGKVPMHKL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Esrra. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 422 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: Esrra (ESRRA Produkte)

Synonyme: err1 antikoerper, erra antikoerper, esrral antikoerper, erralpha antikoerper, nr3b1 antikoerper, MGC80854 antikoerper, ESRRA antikoerper, esrl1 antikoerper, LOC100125507 antikoerper, ERRalpha antikoerper, Err1 antikoerper, Estrra antikoerper, Nr3b1 antikoerper, Errra antikoerper, ERR1 antikoerper, ERRa antikoerper, ESRL1 antikoerper, NR3B1 antikoerper, ESTRRA antikoerper, estrogen-related receptor alpha antikoerper, estrogen related receptor alpha L homeolog antikoerper, estrogen related receptor alpha antikoerper, catsper channel auxiliary subunit zeta antikoerper, estrogen related receptor, alpha antikoerper, esrra antikoerper, esrra.L antikoerper, ESRRA antikoerper, LOC100125507 antikoerper, CATSPERZ antikoerper, Esrra antikoerper

Hintergrund: Esrra binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. It can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. It binds to the C1 region of the lactoferrin gene promoter. It requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
Alias Symbols: ERRalpha, Err1, Estrra, Nr3b1
Protein Interaction Partner: Ubc, Sirt1, Hdac8, Kat2b, Crebzf, Esrrb, Ppargc1a,
Protein Size: 422

Molekulargewicht: 45 kDa

Gen-ID: 26379

NCBI Accession: NM_007953, NP_031979

UniProt: O08580

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha