ESRRA Antikörper (C-Term)

Produktnummer ABIN2779529

Dieses Anti-ESRRA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ESRRA in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Pferd und Meerschweinchen.

Kurzübersicht für ESRRA Antikörper (C-Term) (ABIN2779529)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ESRRA Antikörper

Bindungsspezifität: C-Term

Sequenz: AGRAGPGGGA ERRRAGRLLL TLPLLRQTAG KVLAHFYGVK LEGKVPMHKL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Esrra. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 422 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: Esrra

Hintergrund: Esrra binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. It can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. It binds to the C1 region of the lactoferrin gene promoter. It requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
Alias Symbols: ERRalpha, Err1, Estrra, Nr3b1
Protein Interaction Partner: Ubc, Sirt1, Hdac8, Kat2b, Crebzf, Esrrb, Ppargc1a,
Protein Size: 422

Molekulargewicht: 45 kDa

Gen-ID: 26379

NCBI Accession: NM_007953, NP_031979

UniProt: O08580

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha