MYCN Antikörper (C-Term)

Produktnummer ABIN2779428

Der Kaninchen Polyklonal anti-MYCN Antikörper (ABIN2779428) detektiert spezifisch MYCN in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein und Kaninchen.

Kurzübersicht für MYCN Antikörper (C-Term) (ABIN2779428)

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYCN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MYCN Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: MYCN Antibody - C-terminal region

Sequenz: EDAPPQKKIK SEASPRPLKS VIPPKAKSLS PRNSDSEDSE RRRNHNILER

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 77%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MYCN. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106092

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Andere Bezeichnung: MYCN

Hintergrund:

Background Information: MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas

Gene Name: V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

Alternative Symbols: NMYC, ODED, MODED, N-myc, bHLHe37

Protein Name: N-myc proto-oncogene protein

Molekulargewicht: 50kDa

Gen-ID: 4613

NCBI Accession: NP_005369

UniProt: P04198