MTF1 Antikörper (C-Term)
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- Target Alle MTF1 Antikörper anzeigen
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MTF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MTF1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MTF1
- Top Product
- Discover our top product MTF1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 753 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
- Andere Bezeichnung
- MTF1 (MTF1 Produkte)
- Synonyme
- MTF-1 antikoerper, MTF1 antikoerper, mtf1 antikoerper, MGC86485 antikoerper, Thyls antikoerper, ZRF antikoerper, metal regulatory transcription factor 1 antikoerper, metal-regulatory transcription factor 1 antikoerper, metal-regulatory transcription factor 1 L homeolog antikoerper, metal response element binding transcription factor 1 antikoerper, MTF1 antikoerper, mtf1 antikoerper, mtf1.L antikoerper, Mtf1 antikoerper
- Hintergrund
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The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.
Alias Symbols: ZRF, MTF-1
Protein Interaction Partner: AP1M1, EP300, CREBBP, MT1G,
Protein Size: 753 - Molekulargewicht
- 81 kDa
- Gen-ID
- 4520
- NCBI Accession
- NM_005955, NP_005946
- UniProt
- Q14872
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