MTF1 Antikörper (C-Term)

Produktnummer ABIN2779426

Der Kaninchen Polyklonal anti-MTF1 Antikörper wird verwendet zum Nachweis von MTF1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für MTF1 Antikörper (C-Term) (ABIN2779426)

Target: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MTF1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: MTF1 Antibody - C-terminal region

Sequenz: QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MTF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MTF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105210

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MTF1

Target: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Andere Bezeichnung: MTF1

Hintergrund:

Background Information: The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.

Gene Name: Metal-regulatory transcription factor 1

Alternative Symbols: ZRF, MTF-1

Protein Name: Metal regulatory transcription factor 1

Molekulargewicht: 81kDa

Gen-ID: 4520

NCBI Accession: NP_005946

UniProt: Q14872