IRF5 Antikörper (Middle Region)

Produktnummer ABIN2779405

Dieser Anti-IRF5 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von IRF5 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Pferd, Hund, Meerschweinchen und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für IRF5 Antikörper (Middle Region) (ABIN2779405)

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Pferd, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRF5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: IFFCFGEEWP DRKPREKKLI TVQVVPVAAR LLLEMFSGEL SWSADSIRLQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IRF5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 498 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-IRF5 Antikörper (ABIN2779405)

Coletta, Cullington, Clark, Cleland: "Clinical trials update from European Society of Cardiology meeting 2008: TIME-CHF, BACH, BEAUTIFUL, GISSI-HF, and HOME-HF." in: European journal of heart failure, Vol. 10, Issue 12, pp. 1264-7, (2008) (PubMed).

Details zu IRF5

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Andere Bezeichnung: IRF5

Hintergrund: IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist.
Alias Symbols: SLEB10
Protein Interaction Partner: SGTA, IRF5, COPS7B, COPS4, COPS5, COPS6, COPS8, COPS2, COPS3, UBC, GPS1, TRAF6, MYD88, RGS3, PPM1G, IRF6, HIVEP1, GRB2, CHUK, ALPI, MAVS, GTPBP2, CEP152, GTPBP1, SIN3A, NCOR2, NCOR1, KAT2B, HDAC1, EP300, CREBBP, TRIM15, IKBKE, TBK1, IRF3, XPO1,
Protein Size: 498

Molekulargewicht: 56 kDa

Gen-ID: 3663

NCBI Accession: NM_032643, NP_116032

UniProt: Q13568

Pathways: TLR Signalweg, Autophagie