IRF3 Antikörper (C-Term)
-
- Target Alle IRF3 Antikörper anzeigen
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Schaf, Meerschweinchen, Pferd, Kaninchen
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser IRF3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- SWPQDQPWTK RLVMVKVVPT CLRALVEMAR VGGASSLENT VDLHISNSHP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Sheep: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against IRF3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human IRF3
- Top Product
- Discover our top product IRF3 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 427 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- Andere Bezeichnung
- IRF3 (IRF3 Produkte)
- Synonyme
- irf3 antikoerper, IRF3 antikoerper, C920001K05Rik antikoerper, IRF-3 antikoerper, interferon regulatory factor 3 antikoerper, interferon regulatory factor 7 antikoerper, irf3 antikoerper, IRF3 antikoerper, irf-3 antikoerper, Irf3 antikoerper, IRF7 antikoerper
- Hintergrund
-
IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
Protein Interaction Partner: IRF3, UBC, TMEM173, POLR2A, DEAF1, CREBBP, MAFB, vIRF-3, SMAD4, SMAD2, FOXO1, vIRF-1, EP300, SGTA, PEX19, HSP90AA1, PIAS4, TBK1, TOMM70A, TLR2, MAPK9, MAPK8, MAVS, DDX58, TRAF3, ISG15, TRIM21, PIN1, IRF7, HERC5, IKBKE, CUL1, SUMO2, XIAP, HDAC3, SOCS1, RBL
Protein Size: 427 - Molekulargewicht
- 47 kDa
- Gen-ID
- 3661
- NCBI Accession
- NM_001571, NP_001562
- UniProt
- Q14653
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
-