MAP3K8 Antikörper (N-Term)

Produktnummer ABIN2779366

Dieses Anti-MAP3K8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MAP3K8 in WB. Geeignet für Human, Maus, Rind (Kuh) und Pferd.

Kurzübersicht für MAP3K8 Antikörper (N-Term) (ABIN2779366)

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Reaktivität: Human, Maus, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP3K8 Antikörper

Bindungsspezifität: N-Term

Sequenz: ASEEPAVYEP SLMTMCQDSN QNDERSKSLL LSGQEVPWLS SVRYGTVEDL

Homologie: Cow: 75%, Horse: 87%, Human: 100%, Mouse: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against MAP3K8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 467 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAP3K8

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Andere Bezeichnung: MAP3K8

Hintergrund: MAP3K8 is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was
Alias Symbols: COT, EST, ESTF, FLJ10486, TPL2, Tpl-2, c-COT, MEKK8
Protein Interaction Partner: RELA, MAP2K1, RIPK1, NFKB1, ACY3, STIP1, HSP90AA1, TAB2, TRAF6, TRAF2, CD40, TNIP2, Nedd4, MAP3K14, MAP2K4, BMPR2, CHUK, REL, AKT1, NFKB2, KSR2,
Protein Size: 467

Molekulargewicht: 53 kDa

Gen-ID: 1326

NCBI Accession: NM_005204, NP_005195

UniProt: P41279

Pathways: PI3K-Akt Signalweg, T-Zell Rezeptor Signalweg