FASL Antikörper (Middle Region)

Produktnummer ABIN2779355

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch FASL in WB. Er zeigt eine Reaktivität gegenüber Human, Schwein, Rind (Kuh), Pferd und Kaninchen.

Kurzübersicht für FASL Antikörper (Middle Region) (ABIN2779355)

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reaktivität: Human, Schwein, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FASL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FASL Antikörper

Bindungsspezifität: Middle Region

Sequenz: MHTASSLEKQ IGHPSPPPEK KELRKVAHLT GKSNSRSMPL EWEDTYGIVL

Homologie: Cow: 86%, Horse: 79%, Human: 100%, Pig: 93%, Rabbit: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against FASLG. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 281 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FASL

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Andere Bezeichnung: FASLG

Hintergrund: TNFSF6 is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
Alias Symbols: APT1LG1, CD178, CD95L, FASL, TNFSF6, CD95-L
Protein Interaction Partner: RGS20, TRIP6, NOTCH2NL, KRT40, FAS, CFLAR, FADD, CASP8, NCF1, MACC1, SH3PXD2B, SNX33, SH3RF2, RIMBP3C, SNX18, EPS8L3, ARHGAP9, SAMSN1, MPP4, SRGAP1, BAIAP2L1, NCKIPSD, SNX9, MYO15A, ITSN2, TJP3, OSTF1, SRGAP2, DNMBP, SORBS3, SRGAP3, DOCK4, SH3PXD2A, KALRN
Protein Size: 281

Molekulargewicht: 31 kDa

Gen-ID: 356

NCBI Accession: NM_000639, NP_000630

UniProt: P48023

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity